Configuring FLIRC in the Harmony as an additional device for the Minix Activities, let me to use the Minix U9 profile to manage all buttons directly recognized by the U22, and all remaining buttons not recognized, mapped in the FLIRC profile. It is natively recognized in the Harmony app as an endpoint and has a profile for Kodi (Manifacturer: FLIRC, device:Kodi). This device act as IR receiver and traslate IR signals to keyboard-like stroke. Having a look to posts regarding Minix T5, I found a discussion about the possibility to manage the box using a FLIRC USB dongle and any kind of remote. This is because the HDMI-CEC is enabled on minix to receive TV remote commands This solution works fine if you don't use the TV remote at all, just because, in this case, it may happen the minix starts even if you just want to watch the TV. The only minor thing is that I cant wake up the computer yet. There are some recommendations on the Flirc forums, one of them is a Panasonic TV that I chose and works without any real issues. The only workaround I found was to configure HDMI-CEC on minix and remap the LG remote command on the Harmony. Most importantly, do NOT set up your harmony as a MCE remote but choose a regular device like a TV, preferably of a brand you dont have. No matter which profile I configure on the harmony (U1, U9-H, X8-H Plus), they didn't work.

I mean, all buttons configured on the remote for Minix U1 (ie cursors, volume, channel, back.) are working fine with U22 but Play/Pause, FastForward/Rewind and Stop. Upgrading my U1 to U22, I discovered that all entertainment buttons on my Logitech Harmony One remote stopped to work. I want just to share the solution I found to get rid of my problem:

Logitech harmony flirc